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Table. 2.

Table. 2.

The dosimetric parameters for PTV in supraglottic larynx, hard palate, and tongue cancers using the IMRT and VMAT techniques

Target Parameter Supraglottic larynx Hard palate Tongue P-value




IMRT VMAT IMRT VMAT IMRT VMAT Supra HP Tongue
PTV70 D95% (Gy) 70.00 70.00 70.00 70.00
D98% (Gy) 69.20±0.16 69.07±0.15 69.17±0.08 68.98±0.16 0.011 0.006
D50% (Gy) 72.66±0.34 73.02±0.42 72.48±0.28 73.10±0.36 0.009 0.001
D2% (Gy) 75.38±0.52 76.13±0.61 75.14±0.51 76.31±0.75 0.019 0.001
Mean (Gy) 72.04±1.07 72.29±1.23 71.99±0.34 73.01±0.34 0.548 0.045
Dmax (Gy) 78.54±1.24 79.73±0.96 78.60±1.17 80.77±0.93 0.007 0.001
Dmin (Gy) 63.31±2.19 62.11±2.25 62.77±1.74 61.57±2.15 0.131 0.081
UI 1.07±0.01 1.08±0.01 1.06±0.01 1.08±0.01 <0.001 <0.001
HI 0.072±0.01 0.071±0.01 0.081±0.01 0.078±0.01 <0.001 <0.001
CI 0.99±0.03 0.99±0.03 0.99±0.01 1.00±0.01 0.791 0.093
CN 0.88±0.03 0.90±0.03 0.92±0.03 0.93±0.03 0.972 0.667
PTV63 D95% (Gy) 64.01±0.91 63.91±1.18 0.511
D98% (Gy) 62.95±0.98 62.67±1.45 0.197
D50% (Gy) 68.65±1.52 69.24±1.46 0.001
D2% (Gy) 74.69±0.79 75.26±0.79 0.006
Mean (Gy) 66.06±1.06 66.19±1.62 0.767
Dmax (Gy) 74.65±1.28 75.29±0.96 0.192
Dmin (Gy) 51.02±3.53 51.35±4.05 0.717
UI 1.15±0.01 1.16±0.02 0.102
HI 0.171±0.01 0.168±0.02 0.032
CI 0.99±0.03 0.98±0.03 0.341
CN 0.86±0.05 0.88±0.06 0.142
PTV56 D95% (Gy) 57.78±0.92 57.82±1.04 58.83±0.83 59.70±1.11 0.771 0.055
D98% (Gy) 56.94±0.82 56.79±1.03 57.80±0.72 58.25±0.94 0.423 0.066
D50% (Gy) 63.75±3.64 64.28±3.72 67.40±3.33 68.29±2.72 0.003 0.011
D2% (Gy) 70.63±5.71 71.34±5.62 74.12±1.53 75.13±1.77 0.002 0.002
Mean (Gy) 58.93±1.17 59.04±1.47 62.51±0.91 64.11±1.09 0.769 0.002
Dmax (Gy) 71.35±2.50 70.92±2.73 75.61±1.14 76.55±0.99 0.407 0.008
Dmin (Gy) 46.54±3.60 45.82±2.89 45.65±3.28 46.42±1.79 0.378 0.518
UI 1.21±0.09 1.11±0.37 1.24±0.03 1.24±0.04 0.391 0.576
HI 0.218±0.08 0.214±0.07 0.232±0.02 0.229±0.03 0.051 0.302
CI 1.00±0.01 1.00±0.01 1.00±0.01 0.99±0.01 0.892 0.271
CN 0.72±0.21 0.75±0.21 0.90±0.11 0.92±0.12 <0.001 0.113
PTV60 D95% (Gy) 60.00 60.00
D98% (Gy) 58.93±0.18 58.76±0.25 <0.001
D50% (Gy) 62.84±0.34 63.51±0.45 <0.001
D2% (Gy) 65.44±0.53 66.81±0.74 <0.001
Mean (Gy) 62.69±0.31 63.35±0.41 <0.001
Dmax (Gy) 69.43±1.13 71.67±1.19 <0.001
Dmin (Gy) 50.49±2.27 49.72±3.02 0.871
UI 1.08±0.01 1.1±0.01 <0.001
HI 0.126±0.01 0.123±0.01 <0.001
CI 0.99±0.001 0.99±0.01 0.244
CN 0.88±0.04 0.89±0.04 0.478
PTV54 D95% (Gy) 54.69±0.43 54.48±0.53 0.072
D98% (Gy) 53.89±0.54 53.38±0.58 0.001
D50% (Gy) 57.23±1.31 57.91±1.38 0.001
D2% (Gy) 61.50±2.78 62.69±2.90 0.001
Mean (Gy) 56.81±0.90 57.08±0.59 0.228
Dmax (Gy) 64.16±1.42 64.76±0.99 0.046
Dmin (Gy) 43.06±4.12 43.93±2.89 0.115
UI 1.10±0.05 1.13±0.05 <0.001
HI 0.161±0.05 0.159±0.05 <0.001
CI 1.00±0.001 0.99±0.01 0.078
CN 0.69±0.18 0.72±0.18 0.101

Values are presented in mean±standard deviation.

IMRT, intensity-modulated radiation therapy; VMAT, volumetric modulated arc therapy; PTV, planning target volume; UI, uniformity index; HI, homogeneity index; CI, conformity index; CN, conformation number.

Progress in Medical Physics 2021;32:70-81 https://doi.org/10.14316/pmp.2021.32.3.70
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