Progress in Medical Physics

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Table. 3.

Table. 3.

The dosimetric parameters for OARs in supraglottic larynx, hard palate, and tongue cancers using the IMRT and VMAT techniques

Site OARs Parameter (Gy) IMRT VMAT P-value
Supraglottic larynx Contra lateral parotid Dmean 22.76±1.24 23.41±1.21 <0.001
D50% 18.22±2.28 18.31±0.81 0.853
Brainstem Dmax 33.88±2.57 36.21±2.53 <0.001
Spinal cord Dmax 32.77±1.63 33.92±1.58 0.009
Lips Dmean 32.71±3.74 34.65±2.96 0.016
Larynx Dmean 49.68±1.91 50.47±1.52 0.004
Mandible Dmax 75.83±2.61 76.46±2.19 0.102
Ring (5 cm beyond PTV) Dmean 35.89±3.32 35.48±3.04 0.301
Hard palate Contra lateral parotid Dmean 24.64±2.37 25.43±2.69 0.059
D50% 20.24±0.96 21.75±0.75 0.001
Brainstem Dmax 34.69±3.65 35.68±3.05 0.536
Spinal cord Dmax 34.54±2.35 36.38±2.36 0.029
Lips Dmean 34.72±1.91 35.86±1.57 0.093
Larynx Dmean 47.84±1.04 49.13±0.82 0.011
Mandible Dmax 77.02±1.84 77.32±1.99 0.394
Ring (5 cm beyond PTV) Dmean 36.44±3.79 35.72±4.52 0.062
Tongue Contra lateral parotid Dmean 23.61±1.71 24.76±1.76 <0.001
D50% 19.09±1.76 20.77±1.65 <0.001
Brainstem Dmax 30.64±3.29 30.23±3.87 0.671
Spinal cord Dmax 35.44±1.76 35.65±2.25 0.656
Lips Dmean 34.59±2.41 35.33±1.96 0.206
Larynx Dmean 48.46±1.66 48.71±2.55 0.527
Mandible Dmax 67.41±0.94 68.78±1.28 <0.001
Ring (5 cm beyond PTV) Dmean 32.10±1.58 31.38±1.71 0.001

Values are presented as mean±standard deviation.

OARs, organs-at-risk; IMRT, intensity-modulated radiation therapy; VMAT, volumetric modulated arc therapy; PTV, planning target volume.

Progress in Medical Physics 2021;32:70-81 https://doi.org/10.14316/pmp.2021.32.3.70
© 2021 Progress in Medical Physics