검색
검색 팝업 닫기

Ex) Article Title, Author, Keywords

Article

Original Article

Korean Journal of Medical Physics 2010; 21(2): 174-182

Published online June 25, 2010

Copyright © Korean Society of Medical Physics.

Evaluation of the Feasibility of Applying Metabolic Target Volume in 4D RT Using PET/CT Image

4D RT에서 PET/CT Image를 이용한 Metabolic Target Volume 적용의 유용성 평가

Changuk Kim*, Keum Sung Chun, Kyung Hoon Huh, Yeon Shil Kim, Hong Seok Jang, Won-Gyun Jung*, Lei Xing, Tae-Suk Suh*

김창욱*ㆍ천금성ㆍ허경훈ㆍ김연실ㆍ장홍석ㆍ정원균*ㆍLei Xingㆍ서태석*

*Department of Biomedical Engineering, The Catholic University of Korea College of Medicine, Department of Radiation Oncology, Seoul St Mary's Hospital, Seoul, Korea,Department of Radiation Oncology, Stanford University, California, USA

*가톨릭대학교 의과대학 의공학교실, 서울성모병원 방사선종양학과, Department of Radiation Oncology, Stanford University

Abstract

In this study, we evaluated feasibility of applying MTV (Metabolic Target Volume) to respiratory gated radiotherapy for more accurate treatment using various SUV (Standard Uptake Value) from PET images. We compared VOI (Volume of Interest) images from 50%, 30% and 5% SUV (standard uptake volume) from PET scan of an artificial target with GTV (Gross Tumor Volume) images defined by percentage of respiratory phase from 4D-CT scan for respiratory gated radiotherapy. It is found that the difference of VOI of 30% SUV is reduced noticeably comparing with that of 50% SUV in longitudinal direction with respect to total GTV of 4D-CT image. Difference of VOI of 30% SUV from 4D-PET image defined by respiratory phase from 25% inhalation to 25% exhalation, and GTV from 4D-CT with the same phase is shown below 0.6 cm in maximum. Thus, it is better to use 4D-PET images than conventional PET images for applying MTV to gated RT. From the result that VOI of 5% SUV from 4D-PET agrees well with reference image of 4D-CT in all direction, and the recommendation from department of nuclear medicine that 30% SUV be advised for defining tumor range, it is found that using less than 30% SUV will be more accurate and practical to apply MTV for respiratory gated radiotherapy.

KeywordsPET, 4D PET/CT, Standard uptake value (SUV), 4D-CT, Metabolic target volume (MTV)

Korean Society of Medical Physics

Vol.35 No.1
March 2024

pISSN 2508-4445
eISSN 2508-4453
Formerly ISSN 1226-5829

Frequency: Quarterly

Current Issue   |   Archives

Stats or Metrics

Share this article on :

  • line