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Original Article

Korean Journal of Medical Physics 2012; 23(2): 106-113

Published online June 25, 2012

Copyright © Korean Society of Medical Physics.

Comparison of Dose Distributions Calculated by Anisotropic Analytical Algorithm and Pencil Beam Convolution Algorithm at Tumors Located in Liver Dome Site

간원개에 위치한 종양에 대한 Anisotropic Analyticalal Algorithm과 Pencil Beam Convolution 알고리즘에 따른 전달선량 비교

Byung Do Park, Sang Hoon Jung, Sung Ho Park, Jeong Won Kwak, Jong Hoon Kim, Sang Min Yoon, Seung Do Ahn

박병도ㆍ정상훈ㆍ박성호ㆍ곽정원ㆍ김종훈ㆍ윤상민ㆍ안승도

Department of Radiation Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

울산대학교 의과대학 서울아산병원 방사선종양학교실

Abstract

The purpose of this study is to evaluate the variation of radiation dose distribution for liver tumor located in liver dome and for the interest organs(normal liver, kidney, stomach) with the pencil beam convolution (PBC) algorithm versus anisotropic Analyticalal algorithm (AAA) of the Varian Eclipse treatment planning system, The target volumes from 20 liver cancer patients were used to create treatment plans. Treatment plans for 10 patients were performed in Stereotactic Body Radiation Therapy (SBRT) plan and others were performed in 3 Dimensional Conformal Radiation Therapy (3DCRT) plan. dose calculation was recalculated by AAA algorithm after dose calculation was performed by PBC algorithm for 20 patients. Plans were optimized to 100% of the PTV by the Prescription Isodose in Dose Calculation with the PBC algorithm. Plans were recalculated with the AAA, retaining identical beam arrangements, monitor units, field weighting and collimator condition. In this study, Total PTV was to be statistically significant (SRS: p=0.018, 3DCRT: p=0.006) between PBC and AAA algorithm. and in the case of PTV, ITV in liver dome, plans for 3DCRT were to be statistically significant respectively (p=0.013, p=0.024). normal liver and kidney were to be statistically significant (p=0.009, p=0.037). For the predictive index of dose variation, CVF ratio was to be statistically significant for PTV in the liver dome versus PTV (SRS r=0.684, 3DCRT r=0.732, p<0.01) and CVF ratio for Tumor size was to be statistically significant (SRS r=−0.193, p=0.017, 3DCRT r=0.237, p=0.023).

KeywordsLiver Dome, Lesion coverage factor (CVF), Heterogeneity, Pencil Beam Convolution, Anisotropic Analytical Algorithm

Korean Society of Medical Physics

Vol.35 No.1
March 2024

pISSN 2508-4445
eISSN 2508-4453
Formerly ISSN 1226-5829

Frequency: Quarterly

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