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Original Article

Korean Journal of Medical Physics 2004; 15(2): 84-93

Published online June 25, 2004

Copyright © Korean Society of Medical Physics.

Development of Ideal Model Based Optimization Procedure with Heuristic Knowledge

정위적 방사선 수술에서의 이상표적모델과 경험적 지식을 활용한 수술계획 최적화 방법 개발

Seungjong Oh, Tae-Suk Suh, Ju-Young Song*, Kyoung-Sik Choi, Moon-Chan Kim, and Tae Kyu Lee

오승종·서태석·송주영*·최경식·김문찬·이태규

Department of Biomedical Engineering, The Catholic University of Korea *Department of Radiation Oncology, Chonnam National University Hospital, Department of Neurosurgery, Kangnam St. Mary's Hospital

가톨릭대학교 의과대학 의공학교실, 전남대학교병원 방사선종양학과*, 가톨릭대학교 강남성모병원 신경외과

Abstract

Stereotactic radiosurgery (SRS) is a technique that delivers a high dose to a target region and a low dose to a critical organ through only one or a few irradiations. For this purpose, many mathematical methods for optimization have been proposed. There are some limitations to using these methods: the long calculation time and difficulty in finding a unique solution due to different tumor shapes. In this study, many clinical target shapes were examined to find a typical pattern of tumor shapes from which some possible ideal geometrical shapes, such as spheres, cylinders, cones or a combination, are assumed to approximate real tumor shapes. Using the arrangement of multiple isocenters, optimum variables, such as isocenter positions or collimator size, were determined. A database was formed from these results. The optimization procedure consisted of the following steps: Any shape of tumor was first assumed to an ideal model through a geometry comparison algorithm, then optimum variables for ideal geometry chosen from the predetermined database, followed by a final adjustment of the optimum parameters using the real tumor shape. Although the result of applying the database to other patients was not superior to the result of optimization in each case, it can be acceptable as a plan starting point.

KeywordsSRS, Planning, Optimization, Heuristic, Data base

Korean Society of Medical Physics

Vol.35 No.3
September 2024

pISSN 2508-4445
eISSN 2508-4453
Formerly ISSN 1226-5829

Frequency: Quarterly

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