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Original Article

Korean Journal of Medical Physics 2010; 21(2): 145-152

Published online June 25, 2010

Copyright © Korean Society of Medical Physics.

Performance Measurement of Siemens Inveon PET Scanner for Small Animal Imaging

소동물 영상을 위한 Siemens Inveon PET 스캐너의 성능평가

A Ram Yu*, Jin Su Kim*, Kyeong Min Kim*, Young Sub Lee*, Jong Guk Kim*,Sang Keun Woo*, Ji Ae Park*, Hee Joung Kim, Gi Jeong Cheon*

유아람*ㆍ김진수*ㆍ김경민*ㆍ이영섭*ㆍ김종국*ㆍ우상근*ㆍ박지애*ㆍ김희중ㆍ천기정*

*Molecular Imaging Research Center, Korea Institute Radiological and Medical Science, Seoul, Department of Radiological Science, College of Health Science, Yonsei University, Wonju, Korea

*한국원자력의학원 방사선의학연구소 분자영상연구부, 연세대학교 보건과학대학 방사선학과

Abstract

Inveon PET is a recently developed preclinical PET system for small animal. This study was conducted to measure the performance of Inveon PET as recommended by the NEMA NU 4-2008. We measured the spatial resolution, the sensitivity, the scatter fraction and the NECR using a F-18 source. A 3.432 ns coincidence window was used. A 1 mm3 sized F-18 point source was used for the measurement of spatial resolution within an energy window of 350~625 keV. PET acquisition was performed to obtain the spatial resolution from the center to the 5 cm offset toward the edge of the transverse FOV. Sensitivity, scatter fraction, and NECR were measured within an energy window of 350~750 keV. For measuring the sensitivity, a F-18 line source (length: 12.7 cm) was used with concentric 5 aluminum tubes. For the acquisition of the scatter fraction and the NECR, two NEMA scatter phantoms (rat: 50 mm in diameter, 150 mm in length; mouse: 25 mm in diameter, 70 mm in length) were used and the data for 14 half-lives (25.6 hr) was obtained using the F-18 line source (rat: 316 MBq, mouse: 206 MBq). The spatial resolution of the F-18 point source was 1.53, 1.50 and 2.33 mm in the radial, tangential and axial directions, respectively. The volumetric resolution was 5.43 mm3 in the center. The absolute sensitivity was 6.61%. The peak NECR was 486 kcps @121 MBq (rat phantom), and 1056 kcps @128 MBq (mouse phantom). The values of the scatter fraction were 20.59% and 7.93% in the rat and mouse phantoms, respectively. The performances of the Inveon animal PET scanner were measured in this study. This scanner will be useful for animal imaging.

KeywordsNEMA, Small-animal PET, Performance measurement

Korean Society of Medical Physics

Vol.35 No.2
June 2024

pISSN 2508-4445
eISSN 2508-4453
Formerly ISSN 1226-5829

Frequency: Quarterly

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